Liston, AdrianGoodnow, Christopher2015-12-132015-12-130470021373http://hdl.handle.net/1885/82291The cause of common polygenic autoimmune diseases is poorly understood because of genetic and cellular complexity in humans and animals. We have investigated the mechanisms of two genetic causes of organ-specific autoimmunity by tracking the fate of highKeywords: animal; article; autoimmunity; cytology; genetics; immunology; lymphocyte depletion; mouse; nonobese diabetic mouse; T lymphocyte; thymus; transgenic mouse; Animals; Autoimmunity; Lymphocyte Depletion; Mice; Mice, Inbred NOD; Mice, Transgenic; T-LymphocytGenetic lesions in thymic T cell clonal deletion and thresholds for autoimmunity20052015-12-11