Chemoenzymatic syntheses of (-)-1-deoxymannojirimycin (DMJ) and its naturally occurring 6- O -α-L-rhamnopyranosyl glycoside

Banwell, MartinMa, XinghuaAsano, NaokiIkeda, KyokoLambert, John N2015-12-132015-12-131477-0520http://hdl.handle.net/1885/85804Naturally occurring sugar mimetic alkaloids 1-deoxymannojirimycin (DMJ, 1) and 6-0-α-L-rhamnopyranosyl-DMJ were each prepared in a completely stereoselective manner from the cis-1,2-dihydrocatechol 3. The spectral and physical data derived proved an exceKeywords: Agents; Benzene; Catalysts; Oxidation; Stereochemistry; Synthesis (chemical); Chemoenzymatic synthesis; Deoxymannojirimycin; Rhamnopyradnosyl glycoside; Organic compoundsChemoenzymatic syntheses of (-)-1-deoxymannojirimycin (DMJ) and its naturally occurring 6- O -α-L-rhamnopyranosyl glycoside200310.1039/b304063a2015-12-12