Mander, LewisThomson, Regan2015-12-132015-12-131470-4358http://hdl.handle.net/1885/89310A protocol for the hydroxylation of the 18-methyl group in gibberellins has been developed, as demonstrated by the successful synthesis of 18-hydroxy GA4 methyl ester by means of a tandem process involving the conjugate addition of alkoxide to the α-methKeywords: Addition reactions; Chemical bonds; Derivatives; Hydroxylation; Isomers; Nuclear magnetic resonance spectroscopy; Synthesis (chemical); Gibberellins; Esters200010.1039/b006044p2015-12-12