Kelly, Richard D WRodda, AEDickinson, AdamMahmud, ArsalanNefzger, Christian MLee, WilliamForsythe, John S.Polo, Jose MTrounce, Ian AMcKenzie, MatthewNisbet, DavidSt. John, Justin2015-12-131066-5099http://hdl.handle.net/1885/72427Mitochondrial DNA haplotypes are associated with various phenotypes, such as altered susceptibility to disease, environmental adaptations, and aging. Accumulating evidence suggests that mitochondrial DNA is essential for cell differentiation and the cellKeywords: mitochondrial DNA; octamer transcription factor 4; transcription factor NANOG; transcription factor Sox2; article; cell culture; cell differentiation; cell fate; copy number variation; DNA methylation; embryoid body; embryonic stem cell; energy metabolismMitochondrial DNA haplotypes define gene expression patterns in pluripotent and differentiating embryonic stem cells201310.1002/stem.13132016-02-24