Fernet, CClaisse, MClark-Walker, George2015-12-132015-12-131567-7249http://hdl.handle.net/1885/74817nad genes encoding subunits of the NADH dehydrogenase complex 1 have been revealed in the yeast Debaryomyces (Schwanniomyces) occidentalis. nad1, nad3, nad5, nad6 and most large mitochondrial genes have been located on a circular 41-kb map of mitochondrial DNA from this petite negative species. The genes nad1-nad6 are co-transcribed and the transcription is not inhibited by glucose. Sequences of nad6 and 5′-nad1 compared to homologs in other yeasts indicate better amino acids conservation for nad1 product than for nad6. A cytochrome b deficient mutant dependent on alternative oxidase and functional complex 1 for growth on respirable substrates also exhibits co-transcription of nad1-nad6.Keywords: circular DNA; cytochrome b; glucose; mitochondrial DNA; oxidoreductase; reduced nicotinamide adenine dinucleotide dehydrogenase (ubiquinone); amino acid sequence; article; controlled study; Debaryomyces; Debaryomyces occidentalis; enzyme substrate; enzyme Debaryomyces (Schwanniomyces) occidentalis; Mitochondrial DNA; NADH dehydrogenase genes; Transcription200310.1016/S1567-7249(03)00006-02015-12-11