Hegland, MarkusBurden, ConradSantoso, LuciaMacNamara, ShevarlBooth, Hilary2015-12-070377-0427http://hdl.handle.net/1885/21858An important driver of gene regulatory networks is noise arising from the stochastic nature of interactions of genes, their products and regulators. Thus, such systems are stochastic and can be modelled by the chemical master equations. A major challengeKeywords: Approximation theory; Bifurcation (mathematics); Computer simulation; Multiresolution analysis; Problem solving; Random processes; Gene regulatory networks; Master equations; Sparse grids; Systems biology; Genetic engineering Gene regulatory networks; Master equations; Sparse grids; Systems biology200710.1016/j.cam.2006.02.0532015-12-07