Synthesis of Quinolines, 2-Quinolones, Phenanthridines and 6(5 H )-Phenanthridinones via Palladium[0]-Mediated Ullmann Cross-Coupling of 1-Bromo-2-nitroarenes with β -Halo-enals, -enones or -esters

Banwell, MartinLupton, DavidMa, XinghuaRenner, JensSydnes, Magne2015-12-132015-12-131523-7060http://hdl.handle.net/1885/78379Palladium[0]-mediated Ullmann cross-coupling of 1-bromo-2-nitrobenzene (1 R = H) and its derivatives with a range of β-halo-enals, -enones, or -esters readily affords the corresponding β-aryl derivatives, which are converted into the corresponding quinoKeywords: aromatic nitro compound; carbon; ester derivative; palladium; phenanthridine derivative; quinoline derivative; quinolone derivative; titanium tetrachloride; article; chemical reaction; cross coupling reaction; cyclization; drug synthesis; reaction analysiSynthesis of Quinolines, 2-Quinolones, Phenanthridines and 6(5 H )-Phenanthridinones via Palladium[0]-Mediated Ullmann Cross-Coupling of 1-Bromo-2-nitroarenes with β -Halo-enals, -enones or -esters200410.1021/ol04903752015-12-11