Wang, Ting-YiBruggeman, KiaraSheean, Rebecca KTurner, BradleyNisbet, DavidParish, Clare L.2015-12-130021-9258http://hdl.handle.net/1885/70806Background: Tethering proteins onto bioengineered scaffolds enables longterm delivery, however protein stability, release kinetics, and functionality over time remains unknown. Results: Tethered proteins remain stable and functional for several months, capable of activating intracellular signaling pathways and influencing cell fate. Conclusion: Tethered proteins are stable and functional long-term. Significance: Such knowledge may have implications for promoting tissue repair.Characterization of the Stability and Bio-functionality of Tethered Proteins on Bioengineered Scaffolds: Implications for stem cell biology and tissue repair201410.1074/jbc.M113.5373812015-12-11