Hall, Damien2020-09-210301-4622http://hdl.handle.net/1885/210662A different approach is described for analyzing sedimentation equilibrium experiments of indefinitely self-associating systems. The procedure involves application of conservation of mass criteria, along with local evaluation of the weight average molar mass, to generate a polynomial based on a composite pseudo-independent variable. The outlined method does not depend upon non-linear regression to generate a solution, but instead requires evaluation of the roots of a high-order polynomial.This work was jointly funded by an Australian National University Senior Research Fellowship and an Osaka University Cross-Appointment as an Associate Professor. Further grant assistance was provided by the Osaka University Multiscale Structural Biology Program awarded to Prof. Junichi Takagi and Damien Hall.application/pdfen-AUCrown Copyright © 2017 Published by Elsevier B.V.A composite polynomial approach for analyzing the indefinite self-association of macromolecules studied by sedimentation equilibrium201710.1016/j.bpc.2017.06.0022020-06-23