Looi, JeffreyWalterfang, Mark2015-12-101359-4184http://hdl.handle.net/1885/49640The striatum, comprising the caudate nucleus, putamen and nucleus accumbens, occupies a strategic location within cortico-striato-pallido- thalamic-cortical (corticostriatal) re-entrant neural circuits. Striatal neurodevelopment is precisely determined byKeywords: biological marker; caudate nucleus; clinical feature; cytoarchitecture; deafferentation; degenerative disease; endophenotype; genetic association; human; morphology; nerve cell differentiation; nerve cell plasticity; nervous system development; neuroimagi biomarker; morphology; neurodegeneration; neuroimaging; striatumStriatal morphology as a biomarker in neurodegenerativedisease201310.1038/mp.2012.542016-02-24