A new protoberberine alkaloid from Meconopsis simplicifolia (D. Don) Walpers with potent antimalarial activity against a multidrug resistant Plasmodium falciparum strain

Phurpa, WangchukKeller, PaulPyne, Stephen GLie, WilfordWillis, AnthonyRattanajak, RoonglawanKamchonwongpaisan, Sumalee2015-12-100378-8741http://hdl.handle.net/1885/62686Ethnopharmacological relevance The aerial components of Meconopsis simplicifolia (D. Don) Walpers are indicated in Bhutanese traditional medicine for treating malaria, coughs and colds, and the infections of the liver, lung and blood. This study is to valA new protoberberine alkaloid from Meconopsis simplicifolia (D. Don) Walpers with potent antimalarial activity against a multidrug resistant Plasmodium falciparum strain201310.1016/j.jep.2013.09.0522015-12-10