Matthaei, Klaus2015-12-080022-3751http://hdl.handle.net/1885/29400Although genetic manipulations in mice have provided a powerful tool for investigating gene function in vivo, recent studies have uncovered a number of developmental phenomena that complicate the attribution of phenotype to the specific genetic change. AKeywords: cre recombinase; mifepristone; nerve growth factor receptor; tamoxifen; tetracycline; DNA integration; embryo development; epigenetics; Escherichia coli; gene control; gene deletion; gene expression regulation; gene function; gene overexpression; gene tra200710.1113/jphysiol.2007.1349082015-12-08