Ma, XiangYan, QiaoBanwell, MartinWard, Jas2019-10-151523-7060http://hdl.handle.net/1885/176968Aminocyclitol 2, a recently isolated and notable antifungal agent, was prepared from homochiral γ-hydroxycyclohexenone 4, which is itself available in six steps from L-(+)-tartaric acid (3). The well-defined rigidifying effect arising from the 1,2-diacetal protecting group associated with compound 4 and its derivatives allows for high levels of regio- and stereo-chemical control in the manipulation of the cyclitol framework.application/pdfen-AU© 2017 American Chemical SocietyA Total Synthesis of the Antifungal Deoxyaminocyclitol Nabscessin B from l -(+)-Tartaric Acid201810.1021/acs.orglett.7b034952019-05-05