Maleszka, Ryszard2015-12-101740-6757http://hdl.handle.net/1885/66908The social honey bee, Apis mellifera, is an organism of great value for behavioural, ecological and evolutionary studies. It is also an important agricultural insect and a source of allergies. In recent years its usefulness for research communities has been significantly expanded as a result of progress in genomics and epigenomics. While the bee is not to be misjudged as a model for a specific human disease, it complements other invertebrate models in areas of DNA methylation, metaboloepigenetics and is a source of medically and epigenetically active compounds. This article outlines the anticipated benefits flowing from the epigenome-inspired projects in honey bees and draws attention to the most promising avenues that are likely to strengthen the value of this organism in biomedical research.The social honey bee in biomedical research: realities and expectations201410.1016/j.ddmod.2014.06.0012015-12-10