Important effects of neighbouring nucleotides on electron induced DNA single-strand breaks

Loos, Pierre-Francois; Dumont, Elise; Laurent, Adele D; Assfeld, Xavier

Cultural advice

The Australian National University acknowledges, celebrates and pays our respects to the Ngunnawal and Ngambri people of the Canberra region and to all First Nations Australians on whose traditional lands we meet and work, and whose cultures are among the oldest continuing cultures in human history.

Aboriginal and Torres Strait Islander peoples are advised that ANU Library collections may include images, names, voices, and other representations of deceased persons.

Material in the collection may contain terms, language or views that reflect the period in which the item was created and may be considered inappropriate today.

Important effects of neighbouring nucleotides on electron induced DNA single-strand breaks

Date

2009

Authors

Loos, Pierre-Francois

Dumont, Elise

Laurent, Adele D

Assfeld, Xavier

Publisher

Elsevier

Abstract

In this Letter, we present Quantum Mechanics/Molecular Mechanics (QM/MM) calculations on molecules containing a 2-deoxycytidine-3′-monophosphate moiety (3′-dCMPH). In particular, we examine the effect that including neighbouring nucleotides at the Mol