A chemoenzymatic total synthesis of (+)-amabiline

Findlay, Alison; Banwell, Martin

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A chemoenzymatic total synthesis of (+)-amabiline

Date

2009

Authors

Findlay, Alison

Banwell, Martin

Publisher

American Chemical Society

Abstract

The readily available and enzymatically derived cis-1,2-dihydrocatechol 3 has been converted, over 15 steps, into (+)-amabiline, the nonnatural enantiomeric form of a crinine-type alkaloid.