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DDX3X: stressing the NLRP3 inflammasome

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Date

2019

Authors

Fox, Daniel
Man, Si Ming

Journal Title

Journal ISSN

Volume Title

Publisher

Kexue Chubaneshe/Science Press

Abstract

Stress granules and inflammasomes are intracellular complexes that assemble in response to cellular stress signals, enabling cells to persist and perish, respectively. In a recent study published in Nature, Samir et al. identify the helicase DDX3X as a central decision maker in the formation of pro-survival stress granules or pro-death NLRP3 inflammasomes.

Description

Keywords

Citation

URI

http://hdl.handle.net/1885/314315

Collections

ANU Research Publications

Source

Cell Research

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1038/s41422-019-0250-8

Restricted until

2099-12-31

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s41422-019-0250-8.pdf (603.22 KB)

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