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IL-5-overexpressing mice exhibit eosinophilia and altered wound healing through mechanisms involving prolonged inflammation

Date

Authors

Leitch, Victoria D

Strudwick, Xanthe L

Matthaei, Klaus

Dent, Lindsay

Cowin, Allison

Publisher

Blackwell Publishing Ltd

Abstract

Leucocytes are essential in healing wounds and are predominantly involved in the inflammatory and granulation stages of wound repair. Eosinophils are granulocytic leucocytes and are specifically regulated by interleukin-5 (IL-5), a cytokine produced by T

Keywords

Keywords: collagen; interleukin 5; animal cell; animal experiment; animal model; animal tissue; article; CD4+ T lymphocyte; cell infiltration; cell type; controlled study; disease exacerbation; eosinophil; eosinophilia; female; inflammation; inflammatory cell; knoc Eosinophil; IL-5; Wound

URI

http://hdl.handle.net/1885/35312

Collections

ANU Research Publications

Source

Immunology and Cell Biology

Type

Journal article

DOI

10.1038/icb.2008.72

Restricted until

2037-12-31

Downloads

File

Description

01_Leitch_IL-5-overexpressing_mice_2009.pdf (467.99 KB)