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The immunomodulatory effects of novel β-oxa, β-thia, and γ-thia polyunsaturated fatty acids on human T lymphocyte proliferation, cytokine production, and activation of protein kinase C and MAPKs

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Authors

Costabile, Maurizio
Hii, Charles
Melino, Michelle
Easton, Christopher
Ferrante, Antonio

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American Association of Immunologists

Abstract

We have recently demonstrated that a novel n-3 long chain polyunsaturated fatty acid (PUFA) (β-oxa 21:3n-3) was a more potent and more selective anti-inflammatory agent than n-3 PUFA. To gain further insights into this technology, we synthesized other no

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Journal of Immunology

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DOI

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2037-12-31