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Differential regulation of the Let-7 family of microRNAs in CD4 + T cells alters IL-10 expression

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Date

2012

Authors

Clancy, Jennifer
Swaminathan, Sanjay
Suzuki, Kazuo
Seddiki, Nabila
Kaplan, Warren
Cowley, Mark J.
Hood, Chantelle
Gelgor, Linda
Cooper, David A
Kelleher, Anthony D

Journal Title

Journal ISSN

Volume Title

Publisher

American Association of Immunologists

Abstract

MicroRNAs (miRNAs) are ∼22-nt small RNAs that are important regulators of mRNA turnover and translation. Recent studies have shown the importance of the miRNA pathway in HIV-1 infection, particularly in maintaining latency. Our initial in vitro studies

Description

Keywords

Keywords: Gag protein; interleukin 10; microRNA; microrna let 7; microRNA let 7b; microRNA let 7c; microRNA let 7d; microRNA let 7e; microRNA let 7f; microRNA let 7g; unclassified drug; 3' untranslated region; adult; article; CD4+ T lymphocyte; cell culture; clinic

Citation

URI

http://hdl.handle.net/1885/78137

Collections

ANU Research Publications

Source

Journal of Immunology

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.4049/jimmunol.1101196

Restricted until

2037-12-31

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Description
01_Clancy_Differential_regulation_of_the_2012.pdf (1.11 MB)

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