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Genome-wide association for fear conditioning in an advanced intercross mouse line

Date

Authors

Parker , Clarissa C

Sokoloff, Greta

Cheng, Riyan

Palmer, Abraham A

Publisher

Springer

Abstract

Fear conditioning (FC) may provide a useful model for some components of post-traumatic stress disorder (PTSD). We used a C57BL/6J × DBA/2J F 2 intercross (n = 620) and a C57BL/6J × DBA/2J F 8 advanced intercross line (n = 567) to fine-map quantitative

Keywords

Keywords: 4 aminobutyric acid A receptor alpha2; 4 aminobutyric acid A receptor beta1; alpha amidating enzyme; brain derived neurotrophic factor receptor; diazepam binding inhibitor; protein bcl 2; advanced intercross line; animal experiment; animal model; article; Advanced intercross lines; Fear conditioning; Fear learning; Genome-wide association; Post-traumatic stress disorder; Quantitative trait loci

URI

http://hdl.handle.net/1885/78231

Collections

ANU Research Publications

Source

Behavior Genetics: an international journal devoted to research in the inheritance of behavior in animals and man

Type

Journal article

DOI

10.1007/s10519-011-9524-8

Restricted until

2037-12-31

Downloads

File

Description

01_Parker _Genome-wide_association_for_2012.pdf (692 KB)