A study of de-gassed oil in water dispersions as potential drug delivery systems

Date

Authors

Francis, Mathew

Pashley, Richard

Publisher

Elsevier

Abstract

The natural hydrophobicity of many drugs makes it very difficult to use them for water-based intravenous injection. This lack of water solubility also hinders the development and testing of new drugs. Clinical tests are often refused if the drug can only

Keywords

Keywords: Controlled drug delivery; Degassing; Drug products; Hydrophobicity; Oils and fats; Polymers; Solubility; Surface active agents; Clinical tests; Hydrophobic drugs; Perfluoroctyl bromide (PFOB); Water-insoluble oil; Dispersions; perfluorooctyl bromide; poly De-gassing; Dispersion; Drug delivery; Emulsion; Hydrophobic

URI

http://hdl.handle.net/1885/83162

Collections

ANU Research Publications

Source

Colloids and Surfaces A: Physicochemical and Engineering Aspects

Type

Journal article

DOI

10.1016/j.colsurfa.2005.02.007

Restricted until

2037-12-31

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Description

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