A Chemoenzymatic Total Synthesis of the Phytotoxic Undecenolide (-)-Cladospolide A

Date

2004

Authors

Banwell, Martin
Loong, David

Journal Title

Journal ISSN

Volume Title

Publisher

Royal Society of Chemistry

Abstract

An eleven-step synthesis of the title compound (1) from biocatalytically-derived and enantiomerically pure 'building blocks' alcohol (R)-(-)-9 and ester 13 is described. Attempts to construct the twelve-membered lactone ring of cladospolide A in a direct

Description

Keywords

Keywords: Biocatalysts; Chromatography; Enzymes; Filtration; Hydrogenation; Stereochemistry; Synthesis (chemical); X ray analysis; Allylic alcohols; Necrosis; Retrosynthetic analysis; Ring-closing metathesis (RCM); Amino acids; Alia; cladospolide a; cladospolide B;

Citation

URI

http://hdl.handle.net/1885/78452

Collections

ANU Research Publications

Source

Organic and Biomolecular Chemistry

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1039/b401829j

Restricted until

DSpace software copyright © 2002-2025 LYRASIS