Mechanisms of Amyloid β Protein-Induced Modification in Ion Transport Systems: Implications for Neurodegenerative Diseases
Date
2001
Authors
Kourie, Joseph
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Kluwer Academic Publishers
Abstract
1. Alzheimer's disease (AD) is a neurodegenerative disorder that affects the cognitive function of the brain. Pathological changes in AD are characterized by the formation of amyloid plaques and neurofibrillary tangles as well as extensive neuronal loss.
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Keywords
Keywords: adenosine triphosphatase (potassium sodium); adenosine triphosphate; amyloid beta protein; calcium channel; calcium ion; chloride channel; chloride ion; potassium channel; potassium ion; reactive oxygen metabolite; sodium channel; sodium ion; Alzheimer di Alzheimer's disease; Beta amyloid; Ion channel diseases; Membrane physiology; Neurodegeneration; Neurofibrillary tangles; Protein aggregation; Senile plaques
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Source
Cellular and Molecular Neurobiology
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Journal article
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2037-12-31
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