The mammalian alphaD-globin gene lineage and a new model for the molecular evolution of alpha-globin gene clusters at the stem of the mammalian radiation

Cooper, Steven; Wheeler, D; De Leo, Alison A; Cheng, Jan-Fang; Holland, Robert A B; Graves, Jennifer; Hope, R

The mammalian alphaD-globin gene lineage and a new model for the molecular evolution of alpha-globin gene clusters at the stem of the mammalian radiation

Date

2006

Authors

Cooper, Steven

Wheeler, D

De Leo, Alison A

Cheng, Jan-Fang

Holland, Robert A B

Graves, Jennifer

Hope, R

Publisher

Academic Press

Abstract

We have explored the evolution of the α-globin gene family by comparative sequence and phylogenetic analyses of mammalian α-globin genes. Our analyses reveal the existence of a new α-globin gene lineage in mammals that is related to the αD-globin gene