IL-21 acts directly on B cells to regulate Bc1-6 expression and germinal center responses
Date
Authors
Linterman, Michelle
Beaton, Laura
Yu, Di
Ramiscal, Roy
Srivastava, Monika
Hogan, Jennifer
Verma, Naresh
Smyth, Mark J
Rigby, Robert
Garcia De Vinuesa, Maria Carola
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Rockefeller University Press
Abstract
During T cell-dependent responses, B cells can either differentiate extrafollicularly into short-lived plasma cells or enter follicles to form germinal centers (GCs). Interactions with T follicular helper (Tfh) cells are required for GC formation and for
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Journal of Experimental Medicine
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Restricted until
2037-12-31