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IL-21 acts directly on B cells to regulate Bc1-6 expression and germinal center responses

Date

2010

Authors

Linterman, Michelle
Beaton, Laura
Yu, Di
Ramiscal, Roy
Srivastava, Monika
Hogan, Jennifer
Verma, Naresh
Smyth, Mark J
Rigby, Robert
Garcia De Vinuesa, Maria Carola

Journal Title

Journal ISSN

Volume Title

Publisher

Rockefeller University Press

Abstract

During T cell-dependent responses, B cells can either differentiate extrafollicularly into short-lived plasma cells or enter follicles to form germinal centers (GCs). Interactions with T follicular helper (Tfh) cells are required for GC formation and for

Description

Keywords

Keywords: immunoglobulin G1; immunoglobulin G2a; interleukin 21; interleukin 21 receptor; protein bcl 6; animal cell; antibody response; article; B lymphocyte; cell growth; cell survival; controlled study; erythrocyte; germinal center; helper cell; memory cell; mou

Citation

URI

http://hdl.handle.net/1885/36453

Collections

ANU Research Publications

Source

Journal of Experimental Medicine

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1084/jem.20091738

Restricted until

2037-12-31

Downloads

File
Description
01_Linterman_IL-21_acts_directly_on_B_cells_2010.pdf (4.54 MB)

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