The heritability of oxycodone reward and concomitant phenotypes in a LG/J x SM/J mouse advanced intercross line

Bryant, Camron D; Guido, Michael A; Kole, Loren A; Cheng, Riyan

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The heritability of oxycodone reward and concomitant phenotypes in a LG/J x SM/J mouse advanced intercross line

Date

2014

Authors

Bryant, Camron D

Guido, Michael A

Kole, Loren A

Cheng, Riyan

Publisher

Blackwell Publishing Ltd

Abstract

The rewarding property of opioids likely contributes to their abuse potential. Therefore, determining the genetic basis of opioid reward could aid in understanding the neurobiological mechanisms of opioid addiction, provided that it is a heritable trait.