Purification and structural analyses of ABCG2

Date

Authors

McDevitt, Christopher A.

Collins, Ricahrd

Kerr, Ian

Callaghan, Richard

Publisher

Elsevier BV

Abstract

ABCG2 is best known as a multidrug transporter capable of conferring resistance to cancer cells. However, the protein is also inherently expressed in numerous barrier tissues and intriguingly within hematopoietic stem cells. Unlike its partners ABCB1 and

Keywords

Keywords: Electron microscopy; Membrane protein solubilisation; Molecular modelling; Multidrug efflux; Multidrug resistance; Oligomerisation; Molecular modeling; Oligomerization; Oligomers; Polymers; Proteins; Solubility; Structural analysis; Animal cell culture; A Electron microscopy; Membrane protein solubilisation; Molecular modelling; Multidrug efflux; Multidrug resistance; Oligomerisation; Structural analysis

URI

http://hdl.handle.net/1885/71235

Collections

ANU Research Publications

Source

Advanced Drug Delivery Reviews

Type

Journal article

DOI

10.1016/j.addr.2008.07.004

Restricted until

2037-12-31

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Description

01_McDevitt_Purification_and_structural_2009.pdf (443.35 KB)