Application of semiempirical quantum chemical methods as a scoring function in docking.

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Vasilyev, Vladislav
Bliznyuk, Andrei

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Springer

Abstract

A crucial point in docking simulations is the scoring function used for estimation of the target-ligand interaction energy. The usual practice is to employ fast but simplified empirical scoring functions. Rigorous quantum chemical methods are too slow to

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Theoretical Chemistry Accounts

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