Depressive symptoms and cardiovascular disease: A population-based study of older adults in rural Burkina Faso

dc.contributor.authorBrinkmann, Ben
dc.contributor.authorPayne, Collin
dc.contributor.authorKohler, Iliana
dc.contributor.authorHarling, Guy
dc.contributor.authorDavies, Justine
dc.contributor.authorWitham, Miles
dc.contributor.authorSiedner, Mark J
dc.contributor.authorSie, Ali
dc.contributor.authorBountogo, Mamadou
dc.contributor.authorOuermi, Lucienne
dc.contributor.authorCoulibaly, Boubacar
dc.contributor.authorBarninghausen, Till
dc.date.accessioned2022-10-10T00:04:28Z
dc.date.available2022-10-10T00:04:28Z
dc.date.issued2020
dc.date.updated2021-11-28T07:21:56Z
dc.description.abstractObjectives To contribute to the current understanding of depressive disorders in sub-Saharan African (SSA) countries by examining the association of depressive symptoms with cardiovascular and cardiometabolic conditions in a population-based study of middle-aged and older adults in rural Burkina Faso. Setting This study was conducted in the Nouna Health and Demographic Surveillance System in north-western Burkina Faso, in a mixed rural and small-town environment. The data were obtained between May and July 2018. Participants Consenting adults over 40 years of age (n=3026). Primary and secondary outcome measures Depressive symptoms were assessed using the Patient Health Questionnaire depression module (PHQ-9). Chronic cardiometabolic conditions were assessed via a lipid panel and glycated haemoglobin measures from serum, alongside anthropometry and blood pressure measurements and a self-reported questionnaire. Multivariable linear regression was used to test the relationship between depressive symptoms and cardiovascular/cardiometabolic conditions after controlling for sociodemographic factors. Results Depressive symptoms were not associated with the metabolic syndrome (standardised beta coefficient=0.00 (95% CI-0.04 to 0.03)), hypertension (beta=0.01 (95% CI-0.02 to 0.05)), diabetes mellitus (beta=0.00 (95% CI-0.04 to 0.04)) and past diagnosis of elevated blood pressure or blood sugar. Prior stroke diagnosis (beta=0.04 (95% CI 0.01 to 0.07)) or heart disease (beta=0.08 (95% CI 0.05 to 0.11)) was positively associated with the standardised PHQ-9 score as were self-reported stroke symptoms. Conclusion Objectively measured cardiometabolic conditions had no significant association with depressive symptoms in an older, poor, rural SSA population, in contrast to observations in high income countries. However, consequences of cardiovascular disease such as stroke and heart attack were associated with depressive symptoms in older adults in Burkina Faso.en_AU
dc.description.sponsorshipFunding for the CRSN Heidelberg Aging Study (CHAS) was provided by the Alexander von Humboldt Foundation through an Alexander von Humboldt Professor award to TB, which is funded by the German Federal Ministry of Education and Research. MW acknowledges support from National Institute for Health Research Newcastle Biomedical Research Centre. GH is supported by a fellowship from the Wellcome Trust and Royal Society (210479/Z/18/Z). CFP acknowledges support from the ANU Futures Scheme.en_AU
dc.format.mimetypeapplication/pdfen_AU
dc.identifier.issn2044-6055en_AU
dc.identifier.urihttp://hdl.handle.net/1885/274387
dc.language.isoen_AUen_AU
dc.provenanceThis is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/ licenses/by/4.0/.en_AU
dc.publisherBMJ Publishing Groupen_AU
dc.rights© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ.en_AU
dc.rights.licenseCreative Commons Attribution 4.0 Unported (CC BY 4.0) licenseen_AU
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en_AU
dc.sourceBMJ Openen_AU
dc.titleDepressive symptoms and cardiovascular disease: A population-based study of older adults in rural Burkina Fasoen_AU
dc.typeJournal articleen_AU
dcterms.accessRightsOpen Accessen_AU
local.bibliographicCitation.issue12en_AU
local.bibliographicCitation.lastpage10en_AU
local.bibliographicCitation.startpage1en_AU
local.contributor.affiliationBrinkmann, Ben, Heidelberg Universityen_AU
local.contributor.affiliationPayne, Collin, College of Arts and Social Sciences, ANUen_AU
local.contributor.affiliationKohler, Iliana, University of Pennsylvaniaen_AU
local.contributor.affiliationHarling, Guy, University of the Witwatersranden_AU
local.contributor.affiliationDavies, Justine, University of Birminghamen_AU
local.contributor.affiliationWitham, Miles, Newcastle Universityen_AU
local.contributor.affiliationSiedner, Mark J, Massachusetts General Hospitalen_AU
local.contributor.affiliationSie, Ali, Centre de Recherche en Sante de Nounaen_AU
local.contributor.affiliationBountogo, Mamadou, Centre de Recherche en Sante de Nounaen_AU
local.contributor.affiliationOuermi, Lucienne, Centre de Recherche en Sante de Nounaen_AU
local.contributor.affiliationCoulibaly, Boubacar, Centre de Recherche en Sante de Nounaen_AU
local.contributor.affiliationBarninghausen, Till, University of Heidelbergen_AU
local.contributor.authoremailu1057660@anu.edu.auen_AU
local.contributor.authoruidPayne, Collin, u1057660en_AU
local.description.notesImported from ARIESen_AU
local.identifier.absfor440305 - Population trends and policiesen_AU
local.identifier.absfor420207 - Major global burdens of diseaseen_AU
local.identifier.ariespublicationa383154xPUB15739en_AU
local.identifier.citationvolume10en_AU
local.identifier.doi10.1136/bmjopen-2020-038199en_AU
local.identifier.scopusID2-s2.0-85098187528
local.identifier.uidSubmittedBya383154en_AU
local.publisher.urlhttps://bmjopen.bmj.com/en_AU
local.type.statusPublished Versionen_AU

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