Peptide fragments of the dihydropyridine receptor can modulate cardiac ryanodine receptor channel activity and sarcoplasmic reticulum Ca2+ release
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Dulhunty, Angela
Curtis, Suzanne
Cengia, Louise
Sakowska, Magdalena
Casarotto, Marco
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Portland Press
Abstract
We show that peptide fragments of the dihydropyridine receptor II-III loop alter cardiac RyR (ryanodine receptor) channel activity in a cytoplasmic Ca 2+-dependent manner. The peptides were Ac (Thr-793-Ala-812 of the cardiac dihydropyridine receptor), As
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Biochemical Journal
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2037-12-31
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