T Cell determinants incorporating β -amino acid residues are protease resistant and remain immunogenic in vivo
Date
Authors
Webb, Andrew
Dunstone, Michelle
Williamson, Nicholas
Price, Jason
de Kauwe, Andrea
Chen, Weisan
Oakley, Aaron
Perlmutter, Patrick
McCluskey, James
Aguilar, Marie-Isabel
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American Association of Immunologists
Abstract
A major hurdle in designing successful epitope-based vaccines resides in the delivery, stability, and immunogenicity of the peptide immunogen. The short-lived nature of unmodified peptide-based vaccines in vivo limits their therapeutic application in the
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Journal of Immunology
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2037-12-31
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