LCCL proteins of apicomplexan parasites
Date
2004
Authors
Dessens, Johannes T.
Sinden, Roberet E.
Claudianos, Charles
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier
Abstract
The LCCL module is a conserved, autonomous protein-folding domain that has recently been found in several extracellular proteins of apicomplexan parasites including Plasmodium, Toxoplasma, Cryptosporidium and Theileria, identifying a new protein family in the Apicomplexa. The expression and structure of these modular proteins has fostered speculation about the roles of these novel molecules in immune evasion. Here, the current data and literature on the members of this protein family are reviewed, with a discussion on their possible roles in host-parasite interaction.
Description
Keywords
Keywords: protein; protein lccl; unclassified drug; Apicomplexa; Cryptosporidium; host parasite interaction; nonhuman; nucleotide sequence; phenotype; phylogeny; Plasmodium; protein domain; protein expression; protein family; protein function; protein structure; re
Citation
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Source
Trends in Parasitology
Type
Journal article
Book Title
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Restricted until
2037-12-31