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Novel HIV IL-4R antagonist vaccine strategy can induce both high avidity CD8 T and B cell immunity with greater protective efficacy

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Authors

Jackson, Ronald
Worley, Matthew
Trivedi, Shubhanshi
Ranasinghe, Charani

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Volume Title

Publisher

Elsevier

Abstract

We have established that the efficacy of a heterologous poxvirus vectored HIV vaccine, fowlpox virus (FPV)-HIV gag/pol prime followed by attenuated vaccinia virus (VV)-HIV gag/pol booster immunisation, is strongly influenced by the cytokine milieu at the

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Source

Vaccine

Book Title

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License Rights

Restricted until

2037-12-31