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Can we really learn from model pathogens?

Date

Authors

Mullbacher, Arno

Regner, Matthias

Wang, Yang

Lee, Eva

Lobigs, Mario

Simon, Markus M

Publisher

Elsevier

Abstract

Cytolytic T (Tc) lymphocytes are the first order response of the adaptive immune system in the recovery from primary viral infections. These effector cells execute their function either by direct cytotoxicity through the Fas or perforin pathway and/or by

Keywords

Keywords: cytokine response modifier A; Fas antigen; FAS ligand; perforin; serine proteinase inhibitor; Cowpox virus; cross reaction; cytokine release; cytotoxicity; Ectromelia virus; effector cell; exocytosis; Flavivirus; gene mutation; homozygosity; immune respon

URI

http://hdl.handle.net/1885/78018

Collections

ANU Research Publications

Source

Trends in Immunology

Type

Journal article

DOI

10.1016/j.it.2004.08.004