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The recombinant dihydropyridine receptor II-III loop and partly structured C region peptides modify cardiac ryanodine receptor activity

Date

2005

Authors

Dulhunty, Angela
Karunasekara, Yamuna
Curtis, Suzanne
Harvey, Peta
Board, Philip
Casarotto, Marco

Journal Title

Journal ISSN

Volume Title

Publisher

Portland Press

Abstract

A physical association between the II-III loop of the DHPR (dihydropryidine receptor) and the RyR (ryanodine receptor) is essential for excitation-contraction coupling in skeletal, but not cardiac, muscle. However, peptides corresponding to a part of the

Description

Keywords

Keywords: Molecular structure; Muscle; Polypeptides; Proteins; Peptides; Ryanodine receptor; Skeletal muscle; Cardiology; 1,4 dihydropyridine receptor; C peptide; calcium; isoprotein; muscle protein; peptide; ryanodine receptor; amino terminal sequence; animal tiss Cardiac muscle; Dihydropyridine receptor; Excitation-contraction coupling; Protein-protein interaction; Ryanodine receptor; Skeletal muscle

Citation

Source

Biochemical Journal

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1042/BJ20041152

Restricted until

2037-12-31