T-cell regulation by casitas B-lineage lymphoma (Cblb) is a critical failsafe against autoimmune disease due to autoimmune regulator (Aire) deficiency

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dc.contributor.authorTeh, Charis
dc.contributor.authorDaley, Stephen
dc.contributor.authorEnders, Anselm
dc.contributor.authorGoodnow, Christopher
dc.date.accessioned2015-12-08T22:40:08Z
dc.date.issued2010
dc.date.updated2016-02-24T11:37:51Z
dc.description.abstractAutoimmune polyendocrinopathy syndrome type 1 (APS1) results from homozygous Aire mutations that cripple thymic deletion of organ-specific T cells. The clinical course in man and mouse is characterized by high variability both in the latent period before
dc.identifier.issn0027-8424
dc.identifier.urihttp://hdl.handle.net/1885/36369
dc.publisherNational Academy of Sciences (USA)
dc.sourcePNAS - Proceedings of the National Academy of Sciences of the United States of America
dc.subjectKeywords: autoimmune regulator protein; CD28 antigen; Fas ligand; transcription factor FOXP3; autoimmune regulator protein; Cbl protein; Cblb protein, mouse; signal transducing adaptor protein; transcription factor; acinar cell; animal cell; animal tissue; article; Anergy; Autoimmunity; Pancreatitis; Tolerance; Ubiquitin ligase
dc.titleT-cell regulation by casitas B-lineage lymphoma (Cblb) is a critical failsafe against autoimmune disease due to autoimmune regulator (Aire) deficiency
dc.typeJournal article
local.bibliographicCitation.issue33
local.bibliographicCitation.lastpage14714
local.bibliographicCitation.startpage14709
local.contributor.affiliationTeh, Charis, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationDaley, Stephen, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationEnders, Anselm, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationGoodnow, Christopher, College of Medicine, Biology and Environment, ANU
local.contributor.authoruidTeh, Charis, u4091587
local.contributor.authoruidDaley, Stephen, u4341424
local.contributor.authoruidEnders, Anselm, u4265664
local.contributor.authoruidGoodnow, Christopher, u9710462
local.description.embargo2037-12-31
local.description.notesImported from ARIES
local.identifier.absfor110703 - Autoimmunity
local.identifier.absseo920108 - Immune System and Allergy
local.identifier.ariespublicationu6800332xPUB135
local.identifier.citationvolume107
local.identifier.doi10.1073/pnas.1009209107
local.identifier.scopusID2-s2.0-77957036387
local.identifier.thomsonID000281287600036
local.type.statusPublished Version

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