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A one-pot three component synthesis of b-nitro-a-amino acids and their N-alkyl derivatives

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Coghlan, Phillip
Easton, Christopher

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Royal Society of Chemistry

Abstract

A water-based condensation of glyoxylic acid, nitroalkanes and amines is described, offering a straightforward synthesis of β-nitro-a-amino acids and their AT-alky! derivatives.

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Royal Chemical Society Journal Perkin Transactions

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