Synthesis of 3-azido-2,3,6-trideoxy-β-D-arabino-hexopyranosyl pyranonaphthoquinone analogues of medermycin

Brimble, Margaret A; Davey, Roger M; McLeod, Malcolm; Murphy, Maureen

Synthesis of 3-azido-2,3,6-trideoxy-β-D-arabino-hexopyranosyl pyranonaphthoquinone analogues of medermycin

Date

2003

Authors

Brimble, Margaret A

Davey, Roger M

McLeod, Malcolm

Murphy, Maureen

Publisher

Royal Society of Chemistry

Abstract

The synthesis of an isomeric mixture of 4-O-acetyl-3-azido-2,3,6-trideoxy-β-D-arabino-hexopyranosyl analogues 6 of the C-glycosylpyranonaphthoquinone antibiotic medermycin is described. The key 3-acetyl-6-(4-O-acetyl-3-azido- 2,3,6-trideoxy-β-D-arabino-