Mechanisms of accelerated immune-mediated diabetes resulting from islet β cell expression of a Fas ligand transgene

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dc.contributor.authorSilva, Diego
dc.contributor.authorPetrovsky, Nikolai
dc.contributor.authorSocha, L
dc.contributor.authorSlattery, Robyn
dc.contributor.authorGatenby, Paul
dc.contributor.authorCharlton, Brett
dc.date.accessioned2015-12-13T23:14:02Z
dc.date.issued2003
dc.date.updated2015-12-12T08:36:42Z
dc.description.abstractNonobese diabetic (NOD) mice transgenic for Fas ligand (FasL) on islet β cells (HIPFasL mice) exhibit an accelerated diabetes distinct from the normal autoimmune diabetes of NOD mice. This study was undertaken to define the mechanism underlying accelerat
dc.identifier.issn0022-1767
dc.identifier.urihttp://hdl.handle.net/1885/88409
dc.publisherAmerican Association of Immunologists
dc.sourceJournal of Immunology
dc.subjectKeywords: Fas antigen; FAS ligand; animal cell; animal experiment; animal model; antigen expression; article; controlled study; diabetes mellitus; histopathology; immunopathogenesis; male; mouse; nonhuman; pancreas islet beta cell; priority journal; transgenic mous
dc.titleMechanisms of accelerated immune-mediated diabetes resulting from islet β cell expression of a Fas ligand transgene
dc.typeJournal article
local.bibliographicCitation.issue10
local.bibliographicCitation.lastpage5002
local.bibliographicCitation.startpage4996
local.contributor.affiliationSilva, Diego, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationPetrovsky, Nikolai, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationSocha, L, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationSlattery, Robyn, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationGatenby, Paul, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationCharlton, Brett, College of Medicine, Biology and Environment, ANU
local.contributor.authoruidSilva, Diego, u3266309
local.contributor.authoruidPetrovsky, Nikolai, a160237
local.contributor.authoruidSocha, L, u3266083
local.contributor.authoruidSlattery, Robyn, u9501178
local.contributor.authoruidGatenby, Paul, u4044018
local.contributor.authoruidCharlton, Brett, u9502624
local.description.embargo2037-12-31
local.description.notesImported from ARIES
local.description.refereedYes
local.identifier.absfor110703 - Autoimmunity
local.identifier.ariespublicationMigratedxPub18093
local.identifier.citationvolume170
local.identifier.scopusID2-s2.0-0037988807
local.type.statusPublished Version

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