Spreading vasodilatation in the murine microcirculation: Attenuation by oxidative stress-induced change in electromechanical coupling

Abstract

Regulation of blood flow in microcirculatory networks depends on spread of local vasodilatation to encompass upstream arteries; a process mediated by endothelial conduction of hyperpolarization. Given that endothelial coupling is reduced in hypertension, Show more