Inflammation location, but not type, determines the increase in TGF-β1 and IGF-1 expression and collagen deposition in IBD intestine

Lawrance, I; Maxwell, Lesley; Doe, W

Inflammation location, but not type, determines the increase in TGF-β1 and IGF-1 expression and collagen deposition in IBD intestine

Date

2001

Authors

Lawrance, I

Maxwell, Lesley

Doe, W

Publisher

Lippincott Williams & Wilkins

Abstract

Background and Aims: Inflammatory bowel disease (IBD) is frequently complicated by extracellular matrix (ECM) changes that may result in fibrosis. Transforming growth factor (TGF)-β1 and insulin-like growth factor (IGF)-1 mediate numerous ECM changes. Ou

Keywords

Keywords: collagen; collagen type 1; collagen type 2; messenger RNA; somatomedin C; transforming growth factor beta1; article; colon Crohn disease; controlled study; disease classification; electron microscopy; enteritis; extracellular matrix; fibrosis; human; huma Collagen; IGF-1; Inflammatory bowel disease; Inflammatory infiltrate; TGF-ß1

URI

http://hdl.handle.net/1885/65039

Collections

ANU Research Publications

Source

Inflammatory Bowel Diseases

Type

Journal article

Full item page

Inflammation location, but not type, determines the increase in TGF-β1 and IGF-1 expression and collagen deposition in IBD intestine

Date

Authors

Journal Title

Journal ISSN

Volume Title

Publisher

Abstract

Description

Keywords

Citation

URI

Collections

Source

Type

Book Title

Entity type

Access Statement

License Rights

DOI

Restricted until