PPARgamma inhibits hepatocellular carcinoma metastases in vitro and in mice

Shen, B; Chu, Eagle S. H.; Zhao, G; Man, K; Wu, Chung W; Cheng, JTY; Li, G; Nie, Y; Lo, CM; Teoh, Narcissus; Farrell, Geoffrey; Sung, Joseph J Y; Yu, J

PPARgamma inhibits hepatocellular carcinoma metastases in vitro and in mice

Date

2012

Authors

Shen, B

Chu, Eagle S. H.

Zhao, G

Man, K

Wu, Chung W

Cheng, JTY

Li, G

Nie, Y

Lo, CM

Teoh, Narcissus

Publisher

Nature Publishing Group

Abstract

Background: We have previously demonstrated that peroxisome proliferator-activated receptor (PPARγ) activation inhibits hepatocarcinogenesis. We aim to investigate the effect of PPARγ on hepatocellular carcinoma (HCC) metastatic potential and explore it