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Roquin: a novel immune regulator that represses ICOS expression and differentiation of self-reactive T cells

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Date

2005

Authors

Linterman, Michelle
Garcia De Vinuesa, Maria Carola

Journal Title

Journal ISSN

Volume Title

Publisher

Ediciones Doyma S.A.

Abstract

Controlled and coordinated expression of T cell costimulatory receptors is critical to elicit optimal immune responses while maintaining self tolerance. CD28 is constitutively expressed on naïve T cells and required for effective T cell priming. Converse

Description

Keywords

Keywords: CD28 antigen; messenger RNA; autoimmunity; cell stimulation; gene mutation; human; immune response; immunoregulation; nonhuman; review; T lymphocyte; upregulation ICOS; Lupus; Roquin; TFH; Type 1 diabetes

Citation

URI

http://hdl.handle.net/1885/83828

Collections

ANU Research Publications

Source

Inmunologia

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

Restricted until

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