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Gasdermins deliver a deadly punch to cancer

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Date

2020

Authors

Shen, Cheng
Pandey, Abhimanu
Man, Si Ming

Journal Title

Journal ISSN

Volume Title

Publisher

Springer Nature

Abstract

The pore-forming gasdermin proteins mediate a lytic and proinflammatory form of cell death called pyroptosis and have been linked to the host defense against infection. Two recent studies published in Nature revealed that induction of pyroptosis in tumor cells promotes anti-tumor activity, highlighting gasdermins as potential new targets in cancer immunotherapy.

Description

Keywords

Citation

URI

http://hdl.handle.net/1885/212381

Collections

ANU Research Publications

Source

Cell Research

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1038/s41422-020-0316-7

Restricted until

2037-12-31

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Description
s41422-020-0316-7.pdf (636.48 KB)

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