Recirculating and germinal center B cells differentiate into cells responsive to polysaccharide-antigens
Date
2003
Authors
Garcia De Vinuesa, Maria Carola
Sze, Daniel M-Y
Cook, Matthew
Toellner, K-M
Klaus, Gerry G.B.
Ball, Jennifer
MacLennan, Ian C M
Journal Title
Journal ISSN
Volume Title
Publisher
Wiley-VCH Verlag GMBH
Abstract
Antibodies against bacterial capsular polysaccharides play a critical protective role. Responses to these antigens can occur without the help or control of T cells and are associated with marginal zone (MZ) B cells. Capsular antigens are diverse and some
Description
Keywords
Keywords: antibody; antigen; bacterial polysaccharide; carbohydrate; epitope; hapten; animal experiment; animal tissue; antibody affinity; antibody response; B lymphocyte differentiation; cell protection; controlled study; cross reaction; germinal center; immunoglo Marginal zone B cell; Memory B cell; Recirculating B cell; Thymus-independent type 2 antigen
Citation
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Source
European Journal of Immunology
Type
Journal article