Diversity of Amyloid β Protein Fragment [1-40]-Formed Channels

Date

Authors

Kourie, Joseph

Henry, Christine

Farrelly, Peter

Publisher

Kluwer Academic Publishers

Abstract

1. The lipid bilayer technique was used to characterize the biophysical and pharmacological properties of several ion channels formed by incorporating amyloid beta protein fragment (AβP) 1-40 into lipid membranes. Based on the conductance, kinetics, sele

Keywords

Keywords: amyloid beta protein; ion channel; potassium chloride; zinc chloride; article; cell membrane conductance; cell membrane transport; channel gating; degenerative disease; human; learning; molecular dynamics; neurobiology; nonhuman; priority journal; signal Alzheimer's disease; Channel-forming peptides; Entangles; Memory and learning; Neurodegenerative diseases; Signal transduction

URI

http://hdl.handle.net/1885/65219

Collections

ANU Research Publications

Source

Cellular and Molecular Neurobiology

Type

Journal article

DOI

10.1023/A:1010995121153

Restricted until

2037-12-31

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File

Description

01_Kourie_Diversity_of_Amyloid_β_Protein_2001.pdf (347.12 KB)