Genetic lesions in thymic T cell clonal deletion and thresholds for autoimmunity
Date
2005
Authors
Liston, Adrian
Goodnow, Christopher
Journal Title
Journal ISSN
Volume Title
Publisher
John Wiley & Sons Inc
Abstract
The cause of common polygenic autoimmune diseases is poorly understood because of genetic and cellular complexity in humans and animals. We have investigated the mechanisms of two genetic causes of organ-specific autoimmunity by tracking the fate of high
Description
Keywords
Keywords: animal; article; autoimmunity; cytology; genetics; immunology; lymphocyte depletion; mouse; nonobese diabetic mouse; T lymphocyte; thymus; transgenic mouse; Animals; Autoimmunity; Lymphocyte Depletion; Mice; Mice, Inbred NOD; Mice, Transgenic; T-Lymphocyt
Citation
Collections
Source
Type
Book chapter
Book Title
Genetics of Autoimmunity