Chemoenzymatic syntheses of (-)-1-deoxymannojirimycin (DMJ) and its naturally occurring 6- O -α-L-rhamnopyranosyl glycoside

Banwell, Martin; Ma, Xinghua; Asano, Naoki; Ikeda, Kyoko; Lambert, John N

Chemoenzymatic syntheses of (-)-1-deoxymannojirimycin (DMJ) and its naturally occurring 6- O -α-L-rhamnopyranosyl glycoside

Date

2003

Authors

Banwell, Martin

Ma, Xinghua

Asano, Naoki

Ikeda, Kyoko

Lambert, John N

Publisher

Royal Society of Chemistry

Abstract

Naturally occurring sugar mimetic alkaloids 1-deoxymannojirimycin (DMJ, 1) and 6-0-α-L-rhamnopyranosyl-DMJ were each prepared in a completely stereoselective manner from the cis-1,2-dihydrocatechol 3. The spectral and physical data derived proved an exce