Nucleosomes containing the histone variant H2A.Bbd organize only 118 base pairs of DNA

Bao, Y; Konesky, Kasey; Park, Young Ju; Rosu, Simona; Dyer, Pamela; Rangasamy, Danny; Tremethick, David; Laybourn, Paul; Luger, Karolin

Nucleosomes containing the histone variant H2A.Bbd organize only 118 base pairs of DNA

Date

2004

Authors

Bao, Y

Konesky, Kasey

Park, Young Ju

Rosu, Simona

Dyer, Pamela

Rangasamy, Danny

Tremethick, David

Laybourn, Paul

Luger, Karolin

Publisher

Oxford University Press

Abstract

H2A.Bbd is an unusual histone variant whose sequence is only 48% conserved compared to major H2A. The major sequence differences are in the docking domain that tethers the H2A-H2B dimer to the (H3-H4)2 tetramer; in addition, the C-terminal tail is absent